She is a three-time winner of the Maratona di Sant'Antonio in Padua and won the 2011 Milan City Marathon.

[2] She won the 18 km Miglianico Tour competition in August,[4] going on to place sixth at the Venice Marathon in October.

Her second career win over the longer distance came at the end of that year, as she topped the rankings at the Reggio Emilia Marathon.

[9] She achieved a career best for the half marathon at the Rome-Ostia race in February 2005, running 1:13:15 and finishing as runner-up to Rosaria Console.

[11] Her performances gained Mancini her first national selection – at the 2005 IAAF World Half Marathon Championships she ended the competition in 51st place.

[14] Her national title in Padua had earned her the opportunity to represent Italy in the marathon at the 2006 European Athletics Championships.

[19][21] Mancini was sixth at the Stramilano in March,[22] but she went on to take a major win at the Milan Marathon the following month.