His family moved to the United States in 1940 where his father performed with the Ringling Bros. and Barnum & Bailey Circus.

[citation needed] In 1976, Truzzi was a founding member of the skeptic organization CSICOP and served as its co-chairman along with Paul Kurtz.

[4] He left CSICOP about a year after its founding, after receiving a vote of no confidence from the group's Executive Council.

[8]Truzzi held that CSICOP researchers sometimes also put unreasonable limits on the standards for proof regarding the study of anomalies and the paranormal.

"[10] The book also stated that the evidence didn't meet the burden of proof demanded for such an extraordinary claim.

[11] Although he was familiar with folie à deux, Truzzi was confident a shared visual hallucination could not be skeptically examined by one of the participators.

In a 1982 interview Truzzi stated that controlled ESP (ganzfeld) experiments had "gotten the right results" maybe 60 percent of the time.

Truzzi remained an advisor to IRVA, the International Remote Viewing Association, from its founding meeting until his death.

[13] Truzzi was Keynote Speaker at the 1st annual National Roller Coaster Conference, "CoasterMania", held at Cedar Point Amusement Park, Sandusky, Ohio, in 1978.

He asserts that the claimant has not borne the burden of proof and that science must continue to build its cognitive map of reality without incorporating the extraordinary claim as a new "fact".

But if a critic asserts that there is evidence for disproof, that he has a negative hypothesis—saying, for instance, that a seeming psi result was actually due to an artifact—he is making a claim and therefore also has to bear a burden of proof.In 1994 Susan Blackmore, a parapsychologist who became more skeptical and eventually became a CSICOP fellow in 1991, described what she termed the "worst kind of pseudoskepticism": There are some members of the skeptics' groups who clearly believe they know the right answer prior to inquiry.

They appear not to be interested in weighing alternatives, investigating strange claims, or trying out psychic experiences or altered states for themselves (heaven forbid!

[17] In 2017, World Scientific released a book edited by Dana Richards about the correspondence between Martin Gardner and Truzzi.

The editor, Richards states in the introduction the conflicts between the two men, their differing goals for CSICOP, and various people in the skeptic and paranormal communities.