Marco Antonio Barrera vs. Manny Pacquiao was a professional boxing match contested on November 15, 2003, for the lineal and The Ring featherweight championship.

Meanwhile Manny Pacquiao, who had made four defences of the IBF super bantamweight belt he had won from Lehlo Ledwaba in June 2001, had spent the past year pursing a fight with Barrera.

[5] Within the first 30 seconds of the bout, Pacquiao slipped to the canvas after Barrera had missed with a punch, which referee Laurence Cole incorrectly ruled as a knockdown.

A cut over Barrera's left eye opened up after an unintentional head butt in the 6th round, he would also be deducted a point in the 9th for hitting on the break.

[9] On November 24, 2003, then Philippine President Gloria Macapagal Arroyo conferred on Pacquiao the Presidential Medal of Merit at the Ceremonial Hall of Malacañang Palace for his knockout victory over the best featherweight boxer in the world.