After spending his early career with the club's youth system, the central midfielder was promoted to the first team for the 2003–2004 season, but was instantly loaned out to Serie C2 side Fano Calcio.

Following his return to Tuscany, after the second loan deal expired, Biagianti was surprisingly sold to another third division club, in the form of F.C.

He started the new season as a regular starter and racked up 15 appearances in all competitions, before transferring to Serie A club, Calcio Catania in January 2006.

Biagianti was scouted by Catania chief, Pierto Lo Monaco in 2005, and negotiations began in December 2005, and led to his January transfer to the Sicilian club in 2006.

In his first half-season with Catania, Biagianti made just 2 league appearances, but in his second season, became a more integral part of the team.

Biagianti, unfortunately missed much of the Serie A 2010-11 campaign due to injury, and made just 13 appearances, his fewest in a season with the Sicilians since his first at the club.

On 29 May 2009, Biagianti received his first call up to the Italy national football team as he was named in the squad for the friendly against Northern Ireland that took place on 6 June 2009.