Marco Oppedisano (born November 20, 1971, in Brooklyn, New York) is an American guitarist and composer whose compositions focus on the innovative use of electric guitar in the genre of electroacoustic music.

In addition to musique concrète, compositions by Oppedisano also consist of "live" electric guitar in combination with a fixed playback of various electronic, acoustic (specifically female voice courtesy of Kimberly Fiedelman) and sampled sounds.

Oppedisano began playing guitar at the age of 12 and was primarily a rock guitarist before entering studies at the Conservatory of Music at Brooklyn College.

"Besides These Walls" won Best Actor and Best Narrative Feature at the 2018 Queens World Film Festival.

[1] Oppedisano's music was also use in the short film, Dead Man Rides Subway by Don Cato.