Pitruzzella has been a part of numerous bands, particularly within the death metal genre, which includes Anomalous[1] Brain Drill, Vile, Vital Remains, The Faceless and others.

His drum lessons continued until he was 13, at which point Pitruzzella's passion for metal was born after hearing his first blast beat.

Pitruzzella practiced for several hours every day after school, playing along with his favourite death metal drummers.

After graduating from high school in 2004, Pitruzzella joined Vörnagar, playing drums on their debut album The Bleeding Holocaust.

In 2006, he created Brain Drill with guitarist Dylan Ruskin, releasing two albums, The Parasites (EP, 2006) and Apocalyptic Feasting (2008) on Metal Blade Records.

In 2009, Jeff Hughell and Pitruzzella released a drum-and-bass death metal EP, titled I Came to Hate.