Marco Van Zyl Wentzel (born 6 May 1979 in George, Western Cape, South Africa) is a rugby union player.
After finishing school, he signed a contract with the SWD Eagles, where Heyneke Meyer was the coach.
He made his debut against France alongside Bakkies Botha and Jean de Villiers.
In 2004, he signed with the Italian outfit Treviso where he played for 3 years, coming back in between for stints with the Free State Cheetahs in 2005 (winning the Currie Cup with them) and the Boland Cavaliers, which won Currie Cup First Division.
He moved to England to represent Leicester Tigers and Leeds Carnegie in the Aviva Premiership, before plying his trade with London Wasps and joining teammate Steve Thompson at the Wycombe-based club in 2011.