Margaret Clara Adele Deneke (1882–1969) was an English pianist, musicologist, choirmaster, and benefactor.

Her portrait, with her sister, now located at Lady Margaret Hall, was painted in watercolour by Hubert Andrew Freeth RA.

[6] She corresponded with the likes of the composer Ralph Vaughan Williams[7] and Helen Keller.

[8] There is now a Deneke Building at Lady Margaret Hall,[9] designed by Giles Gilbert Scott and completed in 1932.

[10] During a recital tour of the United States, which Margaret Deneke undertook regularly to support the college financially, the American philanthropist Mary Stillman Harkness, the wife of Edward Harkness, gave a benefaction to her of £35,000.