Her film debut came in the sword and sandal adventure Fire Monsters Against the Son of Hercules (1962), where she played the female lead alongside Reg Lewis, but it was a string of popular comedies that initially made Lee a star in Italy.

With a blonde, fluffy look modelled after Marilyn Monroe, Lee spent the first half of the 1960s appearing in numerous Italian comedies and parodies – several of which starred the popular comedic duo Franco and Ciccio.

Though she failed the win the role of Tatiana Romanova in From Russia with Love,[3] Lee moved away from comedies and started appearing in a long line of Eurospy films, where she was frequently cast as sexy femme fatales.

Lee's co-star in Circus of Fear, Five Golden Dragons, Coplan Saves His Skin and Venus in Furs was the renowned German actor Klaus Kinski (who was also a regular in Harry Alan Towers productions).

Outside of her work for Towers, Lee didn't appear in any further international films but in 1972 she guest starred in the British television series The Protectors, in the episode "The Numbers Game".