Margaret Mary Pearse (4 August 1878 – 7 November 1968) was an Irish Fianna Fáil politician and teacher.

She tried to set up her own school for infants in 1907 in the family home on Great Brunswick Street and was constantly encouraged by her two brothers, whom assisted her in teaching on many occasions.

[4][5] Margaret, along with her mother Mrs. Pearse, played an intricate part in making the school a comfortable atmosphere for the students.

[7] Following the executions of her brothers in the aftermath of the Easter Rising, Margaret continued to run St. Enda's School.

Margaret was directly involved with the teaching as French teacher to junior pupils, and would often write to them to keep in contact during the holidays.

[9] In 1926, Margaret went to America on a lecture tour with the intention of raising more funds for the school to cover its running costs.

[4] Margaret and her mother constantly fought over how to spend the money and eventually they raised enough to buy the school grounds.

She was proposed for the position by Dr. James J.McCann of 23 Terenure Road.This was seconded by Frank Burke, St. Enda's, Harolds Grange, County Dublin.

[5] Margaret's relationship with her sister was further strained after Mary Brigid published The Home-Life of Pádraig Pearse.

She had founded the Rathfarnham Red Cross branch and she had allowed her home in St. Enda's to be used as a first aid hospital.

The president of Ireland at the time, Éamon de Valera, went to visit her at St. Enda's to congratulate her on her upcoming 90th birthday.

Other visitors included the Minister for Finance Charles Haughey and the Lord Mayor of Dublin Frank Cluskey.

[21] Margaret Pearse died aged 90, unmarried, at the Linden Convalescent Home, Blackrock, Dublin, on 7 November 1968 and was given a state funeral.

The funeral then passed through Rathfarnham village where 200 boys and girls from St. Enda's School lined the route in tribute.