As a practitioner, educator and historian, she made important contributions to Australian architecture during the 19th and 20th most prominently in Western Australia.

[1] Her father, George Pitt Morison, was a well known Australian painter and member of the WA Society of Arts, exhibiting from 1902 and 1906.

In 1929 she returned to Perth and joined an architectural firm established by F. G. B. Hawkins, where she worked on the design of the Atlas Assurance Company Office from 1930 to 1931.

In the early 1930s, Morison joined the Poster Studios, a commercial art business established by architects Harold Krantz, John Oldham and Colin Ednie-Brown.

In 1971, she was employed by the University of Western Australia in the School of Architecture and Fine Arts as a research officer, where she remained until her death in 1985.

[1] The University of Western Australia awards the Margaret Pitt-Morison Memorial Prize to outstanding environmental design students.

[15] The WA Chapter of the Australian Institute of Architects named their annual Margaret Pitt Morison Award for Heritage after her.