On screen she played mother to Gary Cooper (Sergeant York) and James Cagney (White Heat).

Wycherly was born in London, England to a Canadian father and American mother, Dr. and Mrs. J. L. De Wolfe.

Wycherly starred in several popular Broadway plays, including Mixed Marriage(1920), Tobacco Road(1933), Liliom, Six Characters in Search of an Author(1922) and The Thirteenth Chair(1916) (which role she reprised in the 1929 film of the same name).

Her other films include Keeper of the Flame, The Yearling, Random Harvest, Forever Amber, The Man with a Cloak and Johnny Angel starring George Raft.

[2] She was buried at the St Mary Churchyard, Bepton, Chichester District, West Sussex, England.