A member of the House of Antioch-Lusignan, she married John of Montfort, Lord of Tyre, and was granted rule of the city as widow in 1284.
Margaret was the younger child of the Lusignan Cypriot princess Isabella and Henry, member of the Ramnulfid dynasty which ruled the Principality of Antioch.
[2] The Templar of Tyre, who served as her page in 1268, recorded that she was "particularly fair of face" at the time, but that later in life she became "enormously fat" and started to resemble her father.
Margaret and her sister-in-law Eschiva of Ibelin, who ruled Beirut alone since Humphrey's death, quickly moved to secure a truce with him.
[8] She then retired to Cyprus, now ruled by her nephew King Henry II, and entered the monastery of Our Lady of Tyre in Nicosia.