According to the defunct royal constitutions of 1923 and 1938, women were barred from wearing the crown, and Margareta and her sisters would not be in the line of succession to the throne.

On 30 December 2007,[11][12] King Michael designated Margareta as heir presumptive to the defunct throne by an act that is not recognized by the Romanian government and lacks legal validity without approval by Romania's Parliament.

[15] Margareta was born on 26 March 1949 at Clinique de Montchoisi in Lausanne, Switzerland,[7] as the first of King Michael I and Queen Anne's five daughters.

[17][self-published source] During holidays she and her sisters spent time with their grandparents; paternally with Helen, Queen Mother,[5][6] at Villa Sparta in Italy and maternally, with Princess Margaret[5][6] and her husband Prince René of Bourbon-Parma in Copenhagen.

[20] In 1960, she was sent to a boarding school in Old Basing, Hampshire, where she stayed until she was 13; she found it difficult to be away from home but was glad that she became more mature, noting that her English improved later.

Known there as "Margareta de Roumanie", for the first few weeks she felt a depressing "sense of foreignness" but later became active in campus politics, becoming a member of the students' representative council.

[20] In 1979, she then worked for the agencies of the United Nations: The World Health Organization and The United Nations Population Fund, where she joined Social projects in public health, based in Africa and Latin America where she came into contact with suffering and deficiencies of the disadvantaged which was the kick start of her experience of the beginning of a road in humanitarian service, which she has still followed since then.

Concluding that fundamental change was about to occur in Eastern Europe, she moved to Geneva to work with the Romanian Crown Council and the royal family, whose members began preparing themselves for what was to come.

The revolution was the first overthrow of the ruling governmental system since King Michael's coup which he successfully staged in 1944 by arresting members of the military government which supported Nazi Germany.

In 1997 King Michael designated Margareta as successor to "all prerogatives and rights" of his, indicating his desire for a gender-blind succession to the throne;[40] although there was much consideration of altering the line of succession, no actions were taken until 30 December 2007, when King Michael I issued the statutes for the Royal House, called The Fundamental Rules of the Royal House of Romania.

[41] Following the announcement of The Fundamental Rules, King Michael asked the Romanian Government that, should it consider restoring the monarchy, it should also abolish the Salic law of succession.

During these visits she is often accompanied by her husband Prince Radu, who is a special Romanian government representative for Integration, Co-operation and Sustainable Development.

[52] BAE Systems, one of the donors to the Princess Margareta of Romania Foundation, and its representatives have been involved in a corruption scandal involving purchase by the Romanian government of two decommissioned UK Royal Navy frigates (Coventry and London) refurbished by BAE, for which an alleged £7 million bribe was paid,[53] some of which, it has also been alleged,[54] ended up in the pockets of the Hohenzollern royal family to which Margareta belongs.

In an official communiqué sent to the newspaper,[56] Prince Radu denied any such lobbying activities, stating that as patron of the British-Romanian Chamber of Commerce of which BAE Systems is a member, he met with its representatives as well as those of other British companies.

In 2002, it rejected any role for her or her husband in a restored monarchy,[57][58] while in 2003 the Cluj branch of PNŢCD officially invited her to be its electoral candidate to the Senate of the Republic in upcoming elections.

[59][60] Prior to his death, King Michael had not given up the hope for the restoration of the throne: "We are trying to make people understand what Romanian monarchy was and what it can still do.

[62] In December 2017, on the backdrop of the increased capital of trust in the Royal House of Romania, re-emerging with the death of King Michael, the executive chairman of the ruling Social Democratic Party Nicolae Bădălau said that one could organize a referendum on the transition to the monarchical ruling form, arguing that "it is not a bad thing, considering that the countries that have the monarchs are developed countries", being a project of the future.