Margarita Nolasco Santiago is a Puerto Rican politician, senator, and former Mayor of Coamo.
[citation needed] After receiving her bachelor's degree, Nolasco worked for the Puerto Rico Department of Education in Barranquitas High School.
After finishing her master's degree, she worked as a mathematics teacher at the Interamerican University of Puerto Rico in Barranquitas.
After some time, she transferred to the Interamerican University of San Germán where she worked as Director of the General Education Program.
For the 2008 general elections, Nolasco ran for Senator at-large after winning a slot at the PNP primaries.