[9] Hines was the original voice actress for Fleischer's cartoon character Betty Boop, whilst she was touring vaudeville she was heard by vocalist Billy Murray, an employee at Fleischer studio who suggested she was the right choice for the voice of the character[10] she made her who debut in the cartoon short Dizzy Dishes in 1930, studio head Max Fleischer hired Hines, as she was a Helen Kane sound-alike, and Kane was the basis for the character.

Beginning in 1932, Hines also did vocals for Aesop's Film Fables and Tom and Jerry produced by Van Beuren Studios.

Her Van Beuren credits were erroneously attributed to Bonnie Poe, another actress who had worked for Fleischer on Betty Boop cartoons.

Mae Questel, who was Fleischer's voice for Betty Boop and Popeye characters Olive Oyl and Swee'Pea during the mid-1930s, left show business in 1938 to start a family.

[11] The Marry-Go-Round (1943) was Hines' final short as the voice of Olive, with Mae Questel returning to the role in 1944 in The Anvil Chorus Girl.