[1] Manoogian was born in Birmingham, Michigan as the eldest daughter of a utility worker and union leader, and a vocational rehabilitation specialist.
[2] After graduating from Ernest W. Seaholm High School in 2010,[3] Manoogian began her undergraduate work at Michigan State University's James Madison College.
[12][13] Manoogian defeated David Wolkinson – former vice chairman of the Michigan Republican Party and policy director to Governor Rick Snyder – by 56.5% to 43.4%, flipping the district for the first time in 22 years.
[14][15][16] Manoogian was selected as one of seventeen speakers to jointly deliver the keynote address at the 2020 Democratic National Convention nominating Joe Biden and Kamala Harris.
[18] She has been profiled by national and local news outlets in the lead-up to her election for supporting funding for clean water initiatives in her district.