[2] Sittel began her television career in 1997 in her hometown on the program Musical Souvenir on the Penza channel "Our House".

[citation needed] From September 24, 2001, to May 14, 2006, Sittel worked as a daily news presenter on Vesti TV channel Russia-1.

[citation needed] From May 15, 2006, to June 17, 2016, Sittel presented the nightly news with Dmitry Kiselyov[5] (until July 2008)[6] and Andrey Kondrashov (since September 2008).

[citation needed] On 18 March 2022, Sittel, together with Dmitry Guberniev, was the host of the Moscow rally in support of the Russian invasion of Ukraine.

[13][14] In 2006, Maria Sittel and professional dancer Vladislav Borodinov took part in the first season of the television competition Dancing with the Stars in Russia.