[1] In 1921 he moved to Mexico City, and from 1922 to 1923 studied at the Academy of San Carlos under teachers such as José Clemente Orozco, Fernando Leal, Sóstenes Orteaga and Raziel Cabildo.
[1][2] Paredes Limón illustrated numerous books and worked on various pamphlets, magazines and other publications for the cultural movements that emerged in Mexico in the 1930s and 1940s.
When this disintegrated, he founded the Taller de Gráfica Popular along with Gabriel Fernández Ledesma, Pablo O'Higgins, Ángel Bracho, Raúl Anguiano and Leopoldo Méndez.
Although he experimented with oil painting, watercolor and drawing, his mastery of engraving earned him his reputation in Mexican art.
Critics in Mexico have noted that he had an eclectic artistic language and his drawings and engravings focus on maternity and country scenes, still lifes, landscapes and images related to Mexican nationalism.