She studied modern literature at the Sorbonne University in Paris and concluded it by working on a thesis dealing with how to adapt classical novels to make them readable for young kids.

Since her first story, "C'est mieux d'être bleu," published in 1985 in the Astrapi magazine, she has written over 80 books for children, most notably three series, "Emilien," "Nils Hazard" and "L'Espionne."

Alongside the "Emiliens," Murail initiates an adventure series in which Nils Hazard, an eccentric etruscologist and teacher at the Sorbonne University, has to solve murders and strange investigations cases.

Murail widens the range of her production, exploring a slightly fantastic daily life first in "Ma vie a changé" (1997), where a librarian comes to struggling with a domestic elf.

"Golem" begins when Majid Badach, a young boy who lives in Hummingbird Tower on the Moreland estate, wins a computer from Priceshrinkers, apparently a trustworthy company.

Majid's life, along with his teacher's, turn on a dime ... After "Jésus, comme un roman ..." (1997), Murail wrote a six-episode series published by Je Bouquine during the two last months of the second millennium.

She then pays tribute to her favorite novelist and « heavenly father » ("Charles Dickens," 2005), and takes her readers back to 19th-century England with the autobiography of a Victorian illustrator, inspired by the life of Beatrix Potter ("Miss Charity," 2008).

She now uses the strength of experience and current events, whether the topic is undocumented children and the necessarily enshrined school system ("Vive la République!," 2005), or a company and a kindergarten being submitted to the same imperatives of « globalisation » and « working more » ("Papa et maman sont dans un bateau," spring 2009), yet never being short of humor.

Despite the seriousness of the issues in question, her « dramatic pedagogy of life » is neither bleak nor heavy : Murail thinks a fictional work intended for children has no need of sad endings.

Teamed up during five years with primary teacher Christine Thiéblemont from Orléans, then joined by educational counselor Patricia Bucheton, she wrote a reading course book for first graders, the "Bulle" textbook, published by Bordas.

Murail revealed her motives and her contribution to this common experience as a children's writer in an interview that can be found on the website of La Charte des auteurs et illustrateurs jeunesse, an association she is involved in.