François Louis's wife, Marie Thérèse de Bourbon, was the sister of Marie-Anne's mother's husband.

After the death of her husband, Marie Louise Élisabeth led a life of "debauchery" at the Palais du Luxembourg and the Château de La Muette.

Marie Anne secretly married her lover, the Louis de Melun, the Duke of Joyeuse, in 1719.

In 1724, during a hunting party at Marie Anne's ancestral home, the Château de Chantilly, Louis disappeared and his body was never found.

[5] Like her sisters, Louise Anne and Élisabeth Alexandrine, she was buried in the Carmelite Convent of the Faubourg Saint-Jacques in Paris.

[6] Her portrait en Sultane, by Jean-Marc Nattier (1733), "justifying her chic state of undress"[7] (Wallace Collection, London) is a famous example of turquerie.