The École supérieure de jeunes filles (Higher School for Young Women) was founded by Marie Haps in 1919, with the help of Paulin Ladeuze, rector of the Catholic University of Louvain, and the support of Cardinal Mercier.

[3] With the reorganization of higher education in the French Community of Belgium in 1995, Marie Haps was merged into Haute École Léonard de Vinci.

In the short run, plans were made to merge a series of Brussels Catholic institutes of higher education, especially IHECS, ICHEC and the Marie Haps translation-interpreting department, first into Saint-Louis University, and later into UCLouvain.

[10] Classes are held at the Hôtel Beernaert and the Tilleul campus, both shared with the Institut libre Marie Haps which continues higher education in other fields.

All masters programmes have been transferred to Louvain-la-Neuve, founding the Louvain School of Translation and Interpreting (LSTI) within UCLouvain's Faculty of Philosophy, Arts and Letters.

[11] The same year, the Faculty launched a bachelor programme in translation and interpreting of sign language, the only one in Belgium, inaugurated by Minister Jean-Claude Marcourt.

The buildings are shared with the Haute école Léonard de Vinci and are now located on either side of the rue d'Arlon, near the European Parliament.

In addition, it has a faculty administration on the Saint-Louis campus (rue de l'Ommegang) as well as an assistant office for the Dean (Boulevard du Jardin botanique).