Marie Louise d'Orléans (Spanish: María Luisa de Orleans; 26 March 1662 – 12 February 1689) was Queen of Spain from 1679 to 1689 as the first wife of King Charles II.

[1] As a petite-fille de France she was entitled to the attribute of Royal Highness, although, as was customary at court at the palace of Versailles, her style, Mademoiselle d'Orléans, was more often used.

Charming, pretty and graceful, Marie Louise, who was her father's favourite child, had a happy childhood, residing most of the time in the Palais Royal, and at the château de Saint-Cloud situated a few kilometres west of Paris.

Marie Louise spent a lot of time with both her paternal and maternal grandmothers—Anne of Austria, who doted on her and left the bulk of her fortune to her when she died in 1666; and Henrietta Maria, who lived in Colombes.

In July 1679,[2] Marie was informed by her father, Philippe, and uncle, King Louis XIV of her betrothal to Charles II of Spain.

[2][4] The proxy marriage took place at the Palace of Fontainebleau on 30 August 1679; standing for the groom was Mademoiselle d'Orléans' distant cousin Louis Armand de Bourbon, Prince of Conti.