[2] She studied illustration at the Jardin du Roi[3] and with Madeleine Basseporte, of whom little is known outside of her anatomical drawings, and the memoirs of contemporaries.
[4] Frustrated with their rapid putrefaction,[5] and at the suggestion of Basseporte, Bihéron turned her skills towards anatomical wax modeling, becoming a leading and highly recognized practitioner of this art.
[2] She was invited again in 1770, to demonstrate an innovative, very detailed and lifelike model of a pregnant woman, complete with moveable parts and fetuses.
Jakob Jonas Björnståhl wrote to Carl Linnaeus, that: Because the Academie did not support women, Bihéron had to earn a living privately, by exhibiting and selling her models, as well as by teaching.
The King of Denmark was one customer, and Empress Catherine II of Russia another; the latter purchasing Bihéron's complete set of anatomical models.