Maria Manaseina

Maria Mikhaĭlovna Manàsseina, also known as Marie de Manacéïne, was a neuroscientist who specialized in the area of sleep deprivation.

She provided the ministry of Education with research and information on how to control and suppress student protests and revolutionary activity.

However, it is not unreasonable to think —taking into account the difficulties faced by women to establish themselves in the scientific and academic world— that Manàsseina publicly conformed to the ideologies of the government to receive financial support and continue her career.

To conduct this investigation, she worked alongside professor Ivan Romanovich Tarkhanov, who was also interested in sleep disorders.

Further research showed that the effects of sleep deprivation in the puppies included a body temperature decrease of four to six degrees, suggesting a halt in the homeostatis system[4] as well as a reduction of the number of red blood cells, local brain hemorrhages, cerebral ganglion impairment, etc.

Her work had a great impact on the scientific community and many scientists replicated her model: In 1896, the American psychologists George T.W.

[5] In 1898, Italian investigators Lamberto Daddi and Giulio Tarozzi and, separately, Cesare Agostini, expanded Manàsseina’s findings by conducting detailed histopathologic and anatomic analyses of the puppies' brains.

Against the prevailing belief at that time, Manàsseina was the first to claim that the fermentation process is due to the action of enzymes that can be isolated from the yeast cells.

publication is “Le Sommeil, tiers de notre vie” (“Sleeping, a third of the human life”), which was published in 1892.