The following year, Šerifović participated at the Pjesma Mediterana music festival in Budva with the song "Bol do ludila", winning the first prize.

In 2006, she released her second album Bez Ljubavi, which was a year later promoted with her first solo concert at Sava Centar in Belgrade.

On the final on 8 March, she was declared the winner by receiving most televotes and coming second on the jury's vote, and thus became the first Eurovision representative of Serbia since the country restored its independence as a sovereign state in 2006.

[9] Upon returning home, Šerifović was greeted by reportedly 70,000 people in front of the House of the City Assembly of Belgrade.

[15] Šerifović was the subject of a documentary film, titled Ispovest (Confession), in which she reflected on her sexual orientation as well as personal struggles, such as domestic abuse from her father.

[24] Same month she also performed at the National Theater in Belgrade, which saw polarizing reception from the general public and indignation from actors' union.

[29][30] Between March and May 2019, she embarked on a tour called Druga strana ploče, where she sang the covers of her favorite songs from other artists as well as her own hits.

During March 2022, Šerifović held five concerts in Banja Luka, Zagreb and Belgrade under the title Druga strana ploče Vol.3.

[36] In late December 2022, she released the single "Dobar Vam dan", which scored over million views in the first 24 hours.

[38] Šerifović made a guest appearance on the Serbian show Kec na jedanaest on 15 October where she spoke about the album; she revealed how much love and emotions she put in while recording the songs.

She also shared that two of the album's songs, "Pola sunca", featuring Matija Cvek which was also released as a single on 6 October 2023 and "Drugačija" were its highlights.

Furthermore, the article compared her international success to those of tennis players Ana Ivanovic, Jelena Janković and Novak Djokovic.

[50] During an interview held at the show Kec na jedanaest, Šerifović shared that she "feels most at home" in all the countries of former Yugoslavia.