She was the Senior Vice President of the Diagnostic Products Corporation, a medical supplies company founded in 1973 by her late husband, for three decades.
[5] Additionally, she has served on the Board of Directors of Temple Beth Am in Los Angeles, where she is a Hall of Honor inductee and recipient of the Torah Fund Award.
[4] Shortly after her husband's death, she established the Sigi Ziering Institute Exploring the Ethical and Religious Implications of the Holocaust at AJU.
[3] In 2011, she sponsored the Alternative Spring Break to Montevideo, Uruguay, of students associated with Hillel: The Foundation for Jewish Campus Life at the University of California, Los Angeles (UCLA).
[4] In February 2013, she established the US$1 million Marilyn and Sigi Ziering Endowment for the Arts at Shalem College in Jerusalem, Israel.
[10] The fund endows the research of Asa Kasher, a co-author of the Israel Defense Forces's Code of Ethics, and Ruth Gavison, a human rights legal scholar.
[12][13] In 2006, she made a US$3.25 million charitable contribution to the L.A. Opera for the performance of works by artists assassinated by the Nazi regime during the Holocaust.