For her role in The Marvelous Mrs. Maisel, Hinkle was nominated for the Primetime Emmy Award for Outstanding Supporting Actress in a Comedy Series in 2019 and 2020.

She played Sandra Markowitz in A Thousand Clowns from July 14 to August 10, 1996, at the Criterion Center Stage Right.

[1] Hinkle starred on the CBS sitcom Two and a Half Men with Charlie Sheen, Jon Cryer, Angus T. Jones, and later Ashton Kutcher as Alan's neurotic ex-wife, Judith.

This may have been due to commitments to her new role as Samantha Bowers in the NBC drama series Deception with Tate Donovan, Victor Garber and Katherine LaNasa.

[7][clarification needed] Hinkle has had roles in films such as I'm Not Rappaport, Frequency, The Next Big Thing, I Am Sam, and Dark Blue.