The Almada brothers had their own family-run production company that eventually dissolved due to financial troubles from lack of profit.

[2] In 1965 Mario played the role of Bruno Rey in the film Los Jinetes de la Bruja, in which the Almada brothers produced and Fernando acted as protagonist.

He agreed to become co-star alongside Vicente Fernandez (El arracadas, 1977); in drug trafficking based films (La banda del carro rojo, 1976); in literary adaptations (Divinas palabras, 1977); ranchera melodramas, (Mariachi, 1976), and urban melodramas (Para usted jefa, 1979).

[5][3] In his more than 200 films the subject of righteous revenge is something that remains as a constant, and especially in movies directed by Pedro Galindo such as Los desalmados (1970); Todo el horizonte para morir (1970); El pistolero del diablo (1973); in 1981 he reinforced this trend with Cazador de asesinos directed by Jose Luis Urquieta, which is based on the ballad of the same name by the band Cadetes de Linares.

In this decade, however, he changed his usual role of a hero/cowboy figure to a recurring villain in urban action films, highlighted in Peor Que Las Fieras alongside Rogelio Guerra and Yolanda Liévana.

I made films in other genres such as Divinas palabras, La india and they did not succeed, people did not go to see them, they prefer action and that has sustained the industry.

Previously in 1978, Almada, alongside his brother Fernando, had collaborated with the band in the film La Banda del Carro Rojo alongside Pedro Infante Jr. From 1997 to 2001, he played an important role in the Grupo Exterminador album "Narco Corridos 2" where he appeared on the cover and also conducted dialogues for most of the album's songs.

For his contributions to the motion picture industry, Almada has been inducted into the Paseo de las Luminarias in Mexico City.

He played the role of the drug trafficker known as "El Texano", an intermediary between the highland narcotics producers and the people of Jose Reyes.

It is an unusual role for him to take on in his career full of mafia-related films, where he often plays an incorruptible police officer or a peaceful civilian who ends up seeking revenge.