Mario Alberto Guillén Suárez (born 23 March 1968) is a Bolivian industrial engineer, lawyer, and politician who served as Minister of Economy and Public Finance from 2017 to 2019 during the administration of Evo Morales.

From 1995 to 1996, Guillén completed a master's degree in business administration at the Bolivian Catholic University San Pablo.

On 24 June 2017, Luis Arce resigned as minister of economy in order to travel to Brazil to undergo treatment for kidney cancer.

[2][5] Guillén stated that he regarded Arce as a "teacher, companion, and friend" and affirmed his "unwavering commitment to apply the economic model that allowed us to achieve stability.

[6][7] However, on 28 November 2019, the newly installed interim government of Jeanine Áñez removed him from that position and replaced him with Antonio Sivila.