After three years in the NBA Development League, Little began an overseas career that spanned Europe, Asia, the Middle East, and South America.
Little attended George Washington High School in Chicago, Illinois, where as a senior in 2005–06, he averaged 22 points, 12 rebounds, seven assists, three steals and three blocks per game.
[2][4] Little decided to redshirt the 2009–10 season in order to give his surgically repaired lower left leg time to heal.
He remained in the area during the off-season, as he had a four-game stint with Filipino team TNT KaTropa during the 2016 PBA Governors' Cup.
[21] Between March and July 2018, Little played for Guaros de Lara in the Liga Americas and the LPB.
[25] For the 2021–22 season, Little joined Levski Sofia of the Bulgarian National Basketball League (NBL).