Mario Humberto De Luna Saucedo (born 5 January 1988) is a Mexican professional footballer who plays as a centre-back for UAT.
A product of Chivas youth team, CD Tapatio, de Luna made his professional debut on November 9, 2008, against Puebla F.C.
At the 2009 Interliga de Luna replaced the injured Jonny Magallón performing brilliantly in the tournament, although he suffered an injury in the final.
On September 6, 2009, he scored his first goal in the Primera División de México helping Chivas to a 2–2 draw against Puebla.
On February 21, 2013, sister club Chivas USA announced they had acquired Mario de Luna and teammates Giovani Casillas and Edgar Mejia on loan from CD Guadalajara.