[citation needed] He appeared in the action film Exterminator 2 (1984), as the main villain against its protagonist, played by Robert Ginty.

In 1985, he played in the comedy Delivery Boys, was one of the central characters in the action drama South Bronx Heroes, and acted in the dramatic TV film Children of the Night and one episode of the Cosby Show.

Cops, four episodes of L.A. Law, and the Clint Eastwood military film Heartbreak Ridge based on the United States Marine Corps.

Van Peebles directed Malcolm Takes a Shot, a 1991 CBS Schoolbreak Special about an aspiring high-school basketball star whose obstacles include epilepsy and his own arrogance.

He was nominated for a DGA Award by the Directors Guild of America for "Outstanding Directorial Achievement in Dramatic Shows".

[10] That same year, he directed one episode of Gabriel's Fire and acted in the TV film A Triumph of the Heart: The Ricky Bell Story.

In 1993, he starred in and directed the black Western Posse, featuring a large ensemble cast including Woody Strode, Billy Zane, Tiny Lister, Tone Lōc, Big Daddy Kane, Robert Hooks, and many more.

In 1998, he directed and starred in Love Kills, a comedy about a masseur who gets mixed up in the family plots at the mansion of a recently deceased Beverly Hills millionaire.

In 2002, he acted in 10,000 Black Men Named George, two episodes of Robbery Homicide Division , and the TV movie Fiona.

In 2003, he acted in the film The Hebrew Hammer, 44 Minutes: The North Hollywood Shoot-Out, Gang of Roses, and The Street Lawyer.

In 2006, he directed and co-starred in the film Hard Luck, starring Wesley Snipes as the lead, and Cybill Shepherd was also in it.

Snipes plays Lucky, a down on his luck former criminal and drug dealer whose post prison trials and tribulations take him on a wild adventure.

[citation needed] In 2008, he acted in his father's film Confessionsofa Ex-Doofus-ItchyFooted Mutha and 43 episodes of the soap opera All My Children.

[citation needed] He directed one episode of Lost, the documentary Fair Game?, and the film Redemption Road.

The film focuses on five friends as they deal with romance, money, prom, college, sex, bullies, Facebook, fitting in, standing out, and finding themselves.

[citation needed] In 2014, Van Peebles wrote, directed, and acted in Red Sky, an action/thriller film starring Cam Gigandet, Shane West, and Rachael Leigh Cook.

In 2016, he directed the film USS Indianapolis: Men of Courage, based largely on the true story of the loss of the ship in the closing stages of the Second World War and starring Nicolas Cage, Tom Sizemore, and Thomas Jane.

That year, he created and produced the TV series Superstition, directed eight episodes, and acted in ten, and in some of them he performed both roles.

[citation needed] In 2014, Van Peebles filmed a public service video supporting the District of Columbia statehood movement.