She was a frequent collaborator of director Lois Weber.
Orth began her career as a playwright and magazine writer, publishing in Breezy Stories as early as 1917.
[3] Orth went on to write several films with and for Weber, including A Midnight Romance, To Please One Woman, Too Wise Wives, and The Blot.
[4] In 1923, she signed a seven-picture contract at Universal as a scenarist; her efforts at the studio included work on The Price of Pleasure and Dorothy Arzner's The Wild Party.
In 1938, she settled a lawsuit with Republic for releasing a 1937 film called Circus Girl based on her novel.