[1] As a child, Calero participated in school performances at the Academia del Perpetuo Socorro and briefly in the San Juan Children's Choir.
As a teenager she attended the Escuela Libre de Música (Free School of Music) in San Juan where she continued to participate in the dramatic arts.
In 1994, she was named Star Actress of the Year at the 19th festival of the Arts Critics Awards for her role in Tal para cual where she performed with Evelio Taillac.
Calero was concurrently participating in various TV projects such as Aguamarina, starring Ruddy Rodríguez and Leonardo García, Hey Miami and the telenovela Me muero por ti, also filmed in 2000.
A year later, she starred at the Abanico Theater in Coral Gables, Florida in El último de los amantes, the Spanish version of Neil Simon's The Last of the Red Hot Lovers.
Prior to her acting in El último de los amantes, she was recognized by the Office of the Government of Puerto Rico in Miami together with Sully Díaz, Mara Croatto, Yolandita Monge and Adamari López.