Mark Emil D'Onofrio (born March 17, 1969) is an American college football coach and former professional player.

D'Onofrio played collegiately as a linebacker at Pennsylvania State University and thereafter was drafted by the Green Bay Packers of the National Football League (NFL).

[4] On January 6, 2017, D'Onofrio was hired by the Houston Cougars as their defensive coordinator and inside linebackers coach, beginning with the 2017 season.

[5] On November 25, 2018, Major Applewhite announced that D'Onofrio had been relieved of his duties as defensive coordinator at the University of Houston.

[6] In early June 2022, it was reported that D'Onofrio would be hired by Paul Chryst and the Wisconsin Badgers as the inside linebackers coach.