Mark Rudolph MacGuigan (November 5, 1894 – April 4, 1972) was an educator, lawyer, judge and political figure on Prince Edward Island.
He represented 3rd Queens in the Legislative Assembly of Prince Edward Island from 1935 to 1944 as a Liberal.
He was born in Hope River, Prince Edward Island, the son of Peter P. MacGuigan and Annie M. Hughes.
After completing his early education, he taught school from 1910 to 1912, then attended Saint Dunstan's College.
MacGuigan resigned his seat in the provincial assembly after he was named a judge in the Supreme Court of Prince Edward Island, serving until 1967.