Sir Mark Brian Pepys (born 18 September 1944) is a South African-born British academic of medicine.
[6] His nomination reads: Pepys has made seminal contributions in three areas: complement and immune response, the pentraxin proteins, and amyloidosis, and is a leading authority on these subjects in the UK and internationally.
He has pioneered work on the structure, function and clinical applications of the pentraxins, C-reactive protein (CRP) and serum amyloid P component (SAP), and identified most of the known members of this valuable aid to patient management.
He introduced radiolabelled SAP as a diagnostic in-vivo tracer for amyloid, which has revolutionised knowledge of the natural history of amyloidosis and its response to treatment.
Mark Pepys has recently won the 2008 Ernst Chain Prize for his work on amyloid diseases, established by Imperial College London in recognition of leaders in their fields.