In September 1980, Pesce attended Massachusetts Institute of Technology (MIT) for a Bachelor of Science degree, but left in June 1982 to pursue opportunities in the newly emerging high-tech industry.

Working in conjunction with such corporations as Microsoft, Netscape, Silicon Graphics, Sun Microsystems and Sony, Pesce convinced the industry to accept the new protocol as a standard for desktop virtual reality.

[5] This development spring-boarded Pesce into a career which has included extensive writings for both the popular and scientific press, teaching and lecturing at universities, conferences, performances, presentations, and film appearances.

[10] His current major project, however, is Light MooresCloud,[11] an ambient device of 52-LEDs which is a lamp with a LAMP-stack;[12] the trademark pays homage to the inexpensive ubiquitous computing engendered by Moore's Law.

Inspired by the GPIO of a borrowed Raspberry Pi, which he realized allowed web users anywhere on the planet to turn an LED on or off on his machine from their browsers, MooresCloud was brought from concept to prototype by a team in eight weeks.