For the 2018 regular season he was found to be a Top 10 performing home plate umpire in terms of accuracy in calling balls and strikes.

[3] On June 28, 2007, Wegner was behind the plate when Toronto Blue Jay Frank Thomas hit his 500th career home run off Minnesota Twins pitcher Carlos Silva.

[5] On May 30, 2012, Wegner was the target of Chicago White Sox announcer Ken Harrelson for ejecting pitcher Jose Quintana.

Wegner worked his first career no-hitter on July 13, 2013, calling balls and strikes for Tim Lincecum's 148-pitch performance against the San Diego Padres.

[6] On November 1, 2017, Wegner was behind home plate for Game 7 of the World Series, which was won by the Houston Astros by a score of 5‍–‍1 over the host Los Angeles Dodgers.