Markle is a town in Huntington and Wells counties, in the U.S. state of Indiana.

Markle was laid out in 1836, but did not prosper until the railroad was extended to that point some time later.

[6] The Wabash River flows through the south edge of the town.

[7] As of the census[9] of 2010, there were 1,095 people, 433 households, and 282 families living in the town.

31.2% of all households were made up of individuals, and 12.3% had someone living alone who was 65 years of age or older.

The racial makeup of the town was 99.27% White, 0.36% African American, and 0.36% from two or more races.

28.6% of all households were made up of individuals, and 12.0% had someone living alone who was 65 years of age or older.