Marlboro Airport was founded in 1922, the era when barnstormers flew "by the seat of their pants."

It was the oldest continuously operating commercial field in the Commonwealth of Massachusetts until its closure.

There was one fixed-base operator, Don's Flying Service, named for former airport manager Don LaCouture Sr. and offered fixed-wing and helicopter flight instruction, tie-downs and hangar space, and major and minor aircraft repairs.

[citation needed] Chapter 673 of the Experimental Aircraft Association was based at Marlboro Airport.

[5] It had one runway, and at the end of its life averaged 37 flights per day with approximately 40 aircraft based on its field.