There are direct TGV services to, among others, Bordeaux, Marseille, Nice, Lyon, Rennes, Lille, Nantes, Limoges, Toulouse, Montpellier, Orléans, Grenoble, Brussels, and Frankfurt.

Previously, the UK Border Agency operated juxtaposed controls and carried out pre-embarkation immigration checks at the station.

[5][6][7] Eurostar services from the UK to the station were suspended in June 2023, due to complications over new rules with post-Brexit border controls, and are expected not to operate for at least the rest of 2023.

[8] From Marne-la-Vallée–Chessy, train services depart to major French cities such as Lyon, Marseille, Nice, Montpellier, Perpignan, Lille and Strasbourg.

International services operate to Brussels in Belgium, Amsterdam in the Netherlands, London via Lille, and Frankfurt in Germany.