It was completed in 1914 at Broadway and Olive Streets, at 19 stories, designed by the St. Louis architecture partnership of Eames & Young.

The building stands at 20 stories with a 2-story penthouse atop the 20th floor.

A 1915 Annex, also designed by Eames & Young, was razed in 1998.

The Marquette Building was added to the National Register of Historic Places the same year, and was redeveloped for condos in 2007.

The building roof sports a small pool atop the eastern wing and a dog park/ relief area on the western wing, that are available to building residents.