Born in Selbach, Rio Grande do Sul, Marquinhos Gabriel joined Internacional's youth setup in 2007, after spells in minor clubs of the same state.

He was promoted to the main squad in 2009, and made his senior debut on 5 February, coming on as a late substitute in a 4–1 home routing over Canoas for the Campeonato Gaúcho championship.

[1] Marquinhos Gabriel made his Série A debut on 19 August 2009, replacing Luis Bolaños in a 1–2 home loss against Corinthians.

[8] On 17 July, however, he left the club and joined Saudi Professional League side Al Nassr.

[9] On 16 January 2015 Marquinhos Gabriel returned to Brazil, signing a one-year loan deal with Santos.