[6] In 1927, Charles Lindbergh visited the hotel to talk about his historic trans-Atlantic flight from New York to Paris in the Spirit of St. Louis.

In December 2004, the city announced that a million-dollar payment by the chief creditor of the Hotel Syracuse would settle the unpaid property taxes dispute.

More detailed plans became public in December 2005,[9] listing the following plans for the complex: 54 condominiums located in the 1980 tower, 155-room business hotel, 150 Apartments, Restoration of banquet facilities and street-level store-fronts, Rehabilitation of the complex's parking garage, Pool and gym In May 2006, the Hotel Syracuse was sold to another Israeli company, AMERIS Holdings Ltd, as part of a larger package deal, which included other assets acquired from GMUL.

AMERIS Holdings Ltd, controlled by Levi Kushnir and his son Elad, has a large portfolio of development across the globe and specifically in the USA.

Shortly after, the garage was fully renovated (Opened September 1, 2007), and the complex hosted some large-scale events, including the Syracuse Film Festival in April 2007.

Then-mayor Matt Driscoll committed to turning Onondaga Street near the hotel complex into a park, in order to push the development along.

The City of Syracuse began a seizure process against the hotel's Israeli owners, GML, for $500,000 in unpaid taxes.

City officials have been pushing for a hotel to complement the 99,000 square foot Nicholas J. Pirro Convention Center.

In 2015 he began a $57 million restoration project in[14] which gave the hotel 261 new guest rooms and returned all the major historic spaces to their former grandeur.