He played college football for the Kansas State Wildcats winning the Lou Groza Award and twice earning All-American honors.

Gramatica is currently the head coach of the Tampa Bay Strikers in the National Indoor Soccer League (NISL).

[4] In 1996, Gramatica was granted a medical redshirt, after tearing his right anterior cruciate ligament one week before the season opener.

[20] Although he was known for jumping in celebration after every successful field goal attempt, he stopped this practice after his younger brother Bill Gramática tore his right anterior cruciate ligament, while playing for the Arizona Cardinals and celebrating in a similar manner after kicking a field goal.

[22] In the fifteenth game against the New Orleans Saints, he kicked 4-of-4 field goal attempts with a long of 32 yards, before suffering a right hamstring strain in the second half.

[26] In the eighth game against the Carolina Panthers, he scored the 400th career point, while kicking 4-of-4 field goals with a long of 53 yards.

[30] Gramatica gained popularity that allowed him to sign exclusive contracts to make advertisement campaigns for diverse companies.

[3] The $14,500,000-contract signed with the Buccaneers in 2002 ranked him among the best-paid Argentine sportsmen after footballers Hernán Crespo, Juan Verón, and Gabriel Batistuta.

In the eleventh game against the Carolina Panthers, he missed three field goal attempts (one was blocked), contributing to a 14–21 loss.

[35] On 8 December 2004, he was signed by the Indianapolis Colts as a kickoff specialist, to complement kicker Mike Vanderjagt who had a groin injury, while reuniting with his former head coach Tony Dungy.

[39] On 22 September 2006, Gramatica returned to the Colts for depth purposes, after Adam Vinatieri suffered a groin injury.

[41] On 27 November 2006, Gramatica was signed by the Dallas Cowboys, after the team released veteran Mike Vanderjagt.

[43] In the 20–21 Wild Card Round loss against the Seattle Seahawks, he made 2-of-2 field goals and 2-of-2 extra points.

[45][46] On 12 December 2007, Gramatica was signed by the New Orleans Saints to handle the kicking duties for the final three games, after kicker Olindo Mare was injured.

[47] On 23 December, he matched his personal long field goal mark of 55 yards just before halftime in a pivotal game against the Philadelphia Eagles.

[49] In the 2008 preseason, he was challenged by sixth-round draft pick Taylor Mehlhaff for the team's placekicking job.

Gramatica remained the starter as Mehlhaff was waived by the Saints on 30 August during the final roster cuts.

Gramatica was perfect until 21 September, when he missed two critical field goals in a loss to the Denver Broncos.

Just two days after the game against Minnesota, Gramática was placed on season-ending injured reserve with a groin injury on 8 October and the team re-signed Mehlhaff.