In 2022, she won her first WTA Tour singles title at the Rabat Grand Prix in Morocco, and reached her first major semifinal at the French Open.

1, she paired with the Italian man No.1 Lorenzo Musetti as part of the United Cup, reaching the final but lost to Jessica Pegula in singles.

In 2020, she made her Grand Slam debut at the Australian Open, overcoming former Wimbledon finalist Eugenie Bouchard in the qualifiers to reach the main draw before falling to eventual champion, Sofia Kenin, in straight sets.

She became the third Italian woman to reach the Roland Garros semifinals in the Open era, following 2010 champion Francesca Schiavone and 2012 finalist Sara Errani.

Seeded 23rd at the Indian Wells Open and having received a bye, she reached the third round for the first time in her career with a win over Madison Brengle.

At the Miami Open, she went even further, reaching the quarterfinals, the first Italian to get this far in the singles draw at the tournament in a decade, defeating Nao Hibino, Claire Liu and 24th seed Jeļena Ostapenko.

Trevisan became the first Italian to make multiple quarterfinals at the WTA 1000-level during the same season since Flavia Pennetta, Roberta Vinci and Sara Errani did so in 2015.

[13] At the Open de Rouen in April, she defeated four-time Grand Slam winner Naomi Osaka in the first round,[14] before losing her next match to third seed Anhelina Kalinina.

87, she received a wildcard for her home tournament, the WTA 1000 Italian Open, but lost to Yulia Putintseva in straight sets.

[27] Then she made the last eight at the WTA 500 Guadalajara Open with wins over eighth seed Caroline Dolehide[28] and Renata Zarazúa,[29] before losing to qualifier and eventual champion Olivia Gadecki.