During her tenure, Martine Moïse served as president of the Fondasyon Klere Ayiti, a community development organization focused on civic education and women's issues.

[8][9][5] Haiti's Ambassador to the United States, Bocchit Edmond, told reporters that Moïse was "in stable, but critical condition" and arrangements were being made to evacuate her to Miami for treatment.

[6][11] On 10 July, she posted an audio message to her Twitter account, saying her husband was killed in a well-planned attack by a group of "highly trained and heavily armed" individuals, with the assassination being so quick he couldn't say a word.

She accused unnamed people of being behind the assassination of her husband, due to the issue of roads, water, electricity, and the constitutional referendum, so they could stall a democratic transition of power.

Her flight landed at the Toussaint Louverture International Airport in Port-au-Prince, where she was greeted by government officials, including the interim President Claude Joseph.