Marx Röist (1454–1524) was a member of the political elite of Zürich, and from 1517 the second commander of the Papal Swiss Guard.
He participated in most of the Diets of the Confederacy during 1500–1520, and he was the leader of the Swiss delegations to Louis XII of France in 1499 and to Pope Julius II in 1512.
He was knighted after the Battle of Murten in 1476, and served as an officer in all Confederate military actions during 1476 until 1515.
He was nominally the commander of the Papal Swiss Guard from 1517 until his death, but he was deputized by his son, Caspar Röist from 1518.
He died before the conflict with Zwingli escalated, and the city council enacted the decree permitting the removal of saints' images still on the very day of his death, 15 June 1524.